Two New Cyclolignan Glycosides from Acanthus ilicifolius
نویسندگان
چکیده
Acanthus ilicifolius L. (Acanthaceae) is a spiny herb of mangrove widely distributed in southeastern Asia. In traditional Chinese medicine, it is used as an anti-inflammatory and anti-hepatitis agent. Previous pharmaceutical studies on this plant revealed that the crude alcoholic extract of its leaves showed antioxidant, hepatoprotective, antitumour and anticarcinogenic effects [1 – 2]. The constituents of this plant had been previously investigated and shown to contain a triterpenoid saponin [3], 2-benzoxazolinone [4], acanthicifoline [5], five benzoxazinoid glucosides [6], two phenylethanoid glycosides and seven lignan glucosides [7]. Recently we reported the isolation and structural elucidation of a new aliphatic alcohol glycoside, a new and five known phenylethanoid glycosides from the aerial parts of this plant [8]. As part of our continuing search for bioactive natural products from tropical medicinal plants, we now describe the isolation and structural elucidation of two new cyclolignan glycosides (1, 2) from the same plant.
منابع مشابه
Phenylethanoid and aliphatic alcohol glycosides from Acanthus ilicifolius.
A phenylethanoid glycoside (ilicifolioside A) and an aliphatic alcohol glycoside (ilicifolioside B), have been isolated from the aerial parts of Acanthus ilicifolius, together with eight known compounds. Their structures were determined from spectroscopic analyses.
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